HPLC CHEMILUMINESCENCE DETECTION OF METHAMPHETAMINE AND AMPHETAMINE IN BLACK-AND-WHITE HAIR SAMPLES

Black and white hair samples were obtained from black-, gray- (i.e., a mixture of black and white hair) and white-haired methamphetamine (MA ) users, and MA and amphetamine (AP) were determined by HPLC using che miluminescence detection (CL-HPLC). MA and AP were detected in black h air, and were found in the part of the hair that grew during the perio d of MA use. In the same subjects, MA concentrations were lower in whi te hair than in black hair and AP was not detected in white hair. This difference may be related to the affinity of MA and AP for melanin.