THE MOVEMENT OF TRANSFER-RNA THROUGH THE RIBOSOME

The interaction between tRNA and the ribosome during translation, spec ifically during elongation, constitutes an example of the motion and a daptability of living molecules. Recent results obtained by cryoelectr on microscopy of ''naked'' ribosomes and ribosomes in functional bindi ng states shine some light on this fundamental life-sustaining process . inspection of the surface contour of our reconstruction reveals a pr ecise ''lock-and-key'' fit between the intersubunit space and the tRNA molecule.