THE INCORPORATION OF NEOGLYCOLIPIDS INTO K562 CELLS - A MODEL FOR THESTUDY OF CARBOHYDRATE-DEPENDENT CYTOLYSIS OF TARGET-CELLS BY NATURAL-KILLER-CELLS

Authors
KOVALENKO EI SABLINA MA KHAIDUKOV SV KHIROVA EV BOVIN NV
Citation
Ei. Kovalenko et al., THE INCORPORATION OF NEOGLYCOLIPIDS INTO K562 CELLS - A MODEL FOR THESTUDY OF CARBOHYDRATE-DEPENDENT CYTOLYSIS OF TARGET-CELLS BY NATURAL-KILLER-CELLS, Bioorganiceskaa himia, 24(3), 1998, pp. 224-228
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear",Biology
Journal title
Bioorganiceskaa himia → ACNP
ISSN journal
01323423
Volume
24
Issue
3
Year of publication
1998
Pages
224 - 228
Database
ISI
SICI code
0132-3423(1998)24:3<224:TIONIK>2.0.ZU;2-O
Abstract
A model system was developed to study the role of cell surface oligosa ccharides in cytotoxicity mediated by natural killer (NK) cells. Polym eric glycoconjugates Glyc-PAA-PE and Glyc-PAA(Flu)-PE (where Glyc is t he 3-aminopropyl Le(x) residue, PAA is the poly(N-2-hydroxyethylacryla mide) matrix, Flu is the residue of a fluorescein derivative, and PE i s the phosphatidylethanolamine residue) were synthesized, and their as sociation with the membranes of living K562 cells was studied.