OCCUPATION AND THE RISK OF LARYNGEAL-CANCER IN URUGUAY

In a case-control analysis involving 112 patients afflicted by larynge al cancer and 509 controls diagnosed with cancers not related to tobac co and alcohol exposures, we studied the effects of type of employment and of substances present in the workplace on laryngeal cancer risk. Effects were measured relative to those never employed or never expose d to the substances. All analyses were controlled for age, tobacco smo king, and alcohol drinking through unconditional logistic regression a nd stratified analysis. Among job titles, butchers, vintners, bakers, and car assemblers presented elevated risks of laryngeal cancer (OR fo r butchers 2.8, 95% CL 1.1-7.2). Similarly asbestos, mists from strong inorganic acids and pesticide exposures were associated with increase d risks of laryngeal cancer (OR for strong acids 1.8, 95% 1.1-2.9). (C ) 1998 Wiley-Liss, Inc.