STROKES, CUTIS MARMORATA TELANGIECTATICA CONGENITA, AND FACTOR-V-LEIDEN

Cutis marmorata telangiectatica congenita is an uncommon, congenital c utaneous condition typified by persistent cutis marmorata and other as sociated abnormalities. Progressive neurologic complications are gener ally not a feature of the disorder. A case is reported of cutis marmor ata telangiectatica congenita associated with diffuse cerebrovascular infarcts at 7 months of age. Moyamoya-like vascular abnormalities were demonstrated in addition to the factor V Leiden mutation, a congenita l hypercoagulable disorder. This novel case illustrates the importance of evaluating children with strokes for congenital thrombophilic diso rders. (C) 1998 by Elsevier Science Inc. All rights reserved.