DIABETES-MELLITUS, HYPERADRENOCORTICISM, AND HYPOTHYROIDISM IN A DOG

An unusual combination of three endocrinopathies found in one dog is d escribed. A six-year-old, spayed female, mixed-breed dog presented wit h polyuria, polydipsia, polyphagia, and weight loss. She was diagnosed with diabetes mellitus but was suspected of having insulin resistance and was diagnosed subsequently with hyperadrenocorticism. Persistent hypercholesterolemia led to the suspicion and eventual diagnosis of hy pothyroidism. The dog has responded well to medical therapy, and her c linical signs and biochemical changes have resolved, A literature sear ch did not identify a similar-reported polyendocrinopathy.