EARLY DETECTION OF HYDROXYCHLOROQUINE TOXICITY

Background: The combination of electro-oculogram (EOG) and Farnsworth 100 hue (F-100) testing is assessed for the early detection of hydroxy chloroquin toxicity. Methods: We reviewed the records of 522 patients receiving hydroxychloroquin. Baseline and annual EOG and F100 tests we re done with a complete eye exam. Results: An abnormal EOG and F100 oc cured in 15 patients (3%). No patient developed premaculopathy without showing both EOG and F100 abnormalities. Conclusion: Combined EOG and F100 testing may he an effective way to screen for hydroxychloroquin toxicity.