Pg. Jones et al., CLONING AND TISSUE DISTRIBUTION OF THE HUMAN G-PROTEIN BETA-5 CDNA, Biochimica et biophysica acta. Molecular cell research, 1402(3), 1998, pp. 288-291
Heterotrimeric G proteins integrate signals between receptors and effe
ctor proteins. We have cloned the human beta 5 subunit from a human br
ain cDNA library. The clone has a 1059 bp open reading frame and is hi
ghly homologous to the murine clone. In contrast to the brain specific
mouse beta 5, northern analysis showed it to be expressed in multiple
tissues. (C) 1998 Elsevier Science B.V.