F. Sanschagrin et al., MOLECULAR HETEROGENEITY OF THE L-1 METALLO-BETA-LACTAMASE FAMILY FROMSTENOTROPHOMONAS-MALTOPHILIA, Antimicrobial agents and chemotherapy, 42(5), 1998, pp. 1245-1248
We have determined the nucleotide sequence of the blaS gene encoding t
he carbapenem-hydrolyzing L-l beta-lactamase from Stenotrophomonas mal
tophilia GN12873. Analysis of the DNA and deduced amino acid sequences
identified a product of 290 amino acids. Comparisons of the L-l amino
acid sequence with those of other zinc beta-lactamases showed 88.6% i
dentify with the L-1 enzyme from S. maltophilia IID1275 and less than
20% identity with other class B metalloenzymes.