DIFFERENTIAL-EFFECTS OF GAMMA-INTERFERON ON CHLAMYDIA-TRACHOMATIS GROWTH IN POLARIZED AND NONPOLARIZED HUMAN EPITHELIAL-CELLS IN CULTURE

Authors
KANE CD BYRNE GI
Citation
Cd. Kane et Gi. Byrne, DIFFERENTIAL-EFFECTS OF GAMMA-INTERFERON ON CHLAMYDIA-TRACHOMATIS GROWTH IN POLARIZED AND NONPOLARIZED HUMAN EPITHELIAL-CELLS IN CULTURE, Infection and immunity, 66(5), 1998, pp. 2349-2351
Citations number
18
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
66
Issue
5
Year of publication
1998
Pages
2349 - 2351
Database
ISI
SICI code
0019-9567(1998)66:5<2349:DOGOCG>2.0.ZU;2-L
Abstract
The effects of gamma interferon (IFN-gamma) on Chlamydia trachomatis g rowth in polarized epithelial cells were examined. The range of IFN-ga mma concentrations causing aberrant chlamydial growth was wider in pol arized than in nonpolarized cultures. Results indicate that chlamydial growth modulation in polarized cells readily leads to persistence and better reflects in vivo conditions.