Objectives - The aim of this study was to determine the prevalence of
multiple sclerosis in a population in South Hungary. Methods - The dia
gnosis was established with the aid of the Poser diagnostic criteria a
nd the degree of physical disability was determined on the Kurtzke exp
anded disability status scale (EDSS), The present medical state (EDSS
score) was determined from outpatient clinical control tests. The prev
alence, the average age at onset of the disease and the proportions of
the various clinical forms were calculated, and the patients' disabil
ity status was estimated. Results - In 1996, the prevalence was 65/100
,000, and the incidence from January 1, 1995 through December 31, 1996
was 7/100,000/year. Discussion - During a period of 2 years, the numb
er of diagnosed patients has almost doubled. The disease can be recogn
ized in an early stage with a minimal neurological deficit. The develo
pment of the diagnostics necessitates re-examinations with modern diag
nostic procedures. During the last 3 years, the general practitioner s
ystem has been reorganized, and the working relationships between the
clinic and family doctors have developed considerably. A comparison of
the present findings with those in other countries with a similar cli
mate revealed very similar prevalence data.