N. Milanovich et al., ALUMINUM PHTHALOCYANINE TETRASULFONATE IN MCF-10F, HUMAN BREAST EPITHELIAL-CELLS - A HOLE-BURNING STUDY, Biophysical journal, 74(5), 1998, pp. 2680-2688
Laser-induced holes are burned in the absorption spectrum of aluminum
phthalocyanine tetrasulfonate (APT) in MCF-10F, human breast epithelia
l cells. The hole burning mechanism is shown to be nonphotochemical. T
he fluorescence excitation spectra and hole spectra are compared with
those of APT in hyperquenched glassy films of water, ethanol, and meth
anol. The results show that the APT is in an acidic, aqueous environme
nt with a hydrogen-bonded network similar to that of glassy water, but
showing the influence of other cellular components. Pressure shifts o
f holes allow the local compressibility about the APT to be determined
.