Ar. Kolker et al., PLANTAR VERRUCOUS CARCINOMA FOLLOWING TRANSMETATARSAL AMPUTATION AND RENAL-TRANSPLANTATION, Annals of plastic surgery, 40(5), 1998, pp. 515-519
Verrucous carcinoma is a rare, low-grade, well-differentiated squamous
cell carcinoma that may occur anywhere on the skin. It is slow growin
g, enlarges relentlessly, and invades locally. Most cutaneous verrucou
s carcinomas are found on the plantar surface of the foot, and share m
any gross and histological characteristics common to the ubiquitous ve
rruca vulgaris. It is not uncommon for verrucous carcinoma of the sole
to be mistaken for the more common verruca plantaris. The case of a 5
3-year-old white male with plantar verrucous carcinoma following cadav
eric renal transplantation, right popliteal-tibial bypass, and a right
transmetatarsal amputation is presented. Treatment included reamputat
ion followed by reconstruction with a free radial forearm fasciocutane
ous flap. Verrucous carcinoma is a slow-growing but relentlessly invad
ing tumor that is easily misdiagnosed. The extent of early resection i
s often inadequate. We must be aware that certain persistent ''warts''
may represent a form of cancer that is treated differently from commo
n verrucae or other squamous carcinomas.