We report a case of inflammatory cap polyposis of the colon, a rare sy
ndrome, affecting the rectosigmoid. It was observed in a context of mu
cous diarrhea. Endoscopic and radiological features consisted of eleva
ted and umbilicated nodular lesions. Histology revealed polypoid lesio
ns containing elongated crypts with superficial abrasions, covered by
inflammatory and fibrinoid material. Etiopathogenesis of this new synd
rome is unknown.