IMMUNOLOGICAL MECHANISMS IN THE ANTITUMOR EFFECT OF A VACCINE STRAIN OF VENEZUELAN ENCEPHALOMYELITIS VIRUS

Authors
URAZOVA LN GROMOVA AY PERELMUTER VM
Citation
Ln. Urazova et al., IMMUNOLOGICAL MECHANISMS IN THE ANTITUMOR EFFECT OF A VACCINE STRAIN OF VENEZUELAN ENCEPHALOMYELITIS VIRUS, Eksperimental'naa onkologia, 20(1), 1998, pp. 60-65
Citations number
16
Categorie Soggetti
Oncology
Journal title
Eksperimental'naa onkologia → ACNP
ISSN journal
02043564
Volume
20
Issue
1
Year of publication
1998
Pages
60 - 65
Database
ISI
SICI code
0204-3564(1998)20:1<60:IMITAE>2.0.ZU;2-6
Abstract
The attenuated strain of Venezuelan encephalomyelitis virus was shown to cause a pronounced inhibition of Ehrlich adenocarcinoma growth in B ALB/c mice. Direct lytic influence and complex activation of immunolog ic rejection (tumor cell antigen modification and non-specific immunom odulation) are the basis of antitumor effect of this virus.