PRIMARY EPITOPES OF CHICKEN EGG-YOLK ANTIBODIES TO PEPTIDOPHOSPHOGALACTOMANNAN

Authors
TUEKAM BA BONETTI SJ GANDER JE
Citation
Ba. Tuekam et al., PRIMARY EPITOPES OF CHICKEN EGG-YOLK ANTIBODIES TO PEPTIDOPHOSPHOGALACTOMANNAN, Clinical and diagnostic laboratory immunology, 5(3), 1998, pp. 404-406
Citations number
32
Categorie Soggetti
Immunology,"Infectious Diseases",Microbiology
Journal title
Clinical and diagnostic laboratory immunology → ACNP
ISSN journal
1071412X
Volume
5
Issue
3
Year of publication
1998
Pages
404 - 406
Database
ISI
SICI code
1071-412X(1998)5:3<404:PEOCEA>2.0.ZU;2-X
Abstract
Egg yolks from hens immunized with peptidophosphogalactomannan (pPGalM an(ii)), which contains 10 phosphocholine diester residues and is secr eted by Penicillium fellutanum, contain antibodies against 5-O-beta-D- galactofuranosyl epitopes. These epitopes were the only significant de terminants in pPGalMan(ii). Approximately 60-fold less pPGalMan(ii) (1 .6 mu M galactofuran chains) was required for 50% inhibition than gala ctofurano-oligosaccharides or pPGalMan containing two galactofuranosyl residues per chain.