EFFECT OF CYTOKINES ON ANTICRYPTOCOCCAL ACTIVITY OF HUMAN MICROGLIAL CELLS

Authors
LIPOVSKY MM JULIANA AE GEKKER G HU SX HOEPELMAN AIM PETERSON PK
Citation
Mm. Lipovsky et al., EFFECT OF CYTOKINES ON ANTICRYPTOCOCCAL ACTIVITY OF HUMAN MICROGLIAL CELLS, Clinical and diagnostic laboratory immunology, 5(3), 1998, pp. 410-411
Citations number
18
Categorie Soggetti
Immunology,"Infectious Diseases",Microbiology
Journal title
Clinical and diagnostic laboratory immunology → ACNP
ISSN journal
1071412X
Volume
5
Issue
3
Year of publication
1998
Pages
410 - 411
Database
ISI
SICI code
1071-412X(1998)5:3<410:EOCOAA>2.0.ZU;2-W
Abstract
The effect of selected cytokines on the antifungal activity of human m icroglia was studied with encapsulated and acapsular strains of Crypto coccus neoformans. None of the cytokines tested increased the fungista tic activity of microglia, suggesting that killing of cryptococci with in the central nervous system is dependent on other host defense mecha nisms.