Familial hairy cell leukemia (HCL) occurs rarely, and HCL occurring in
association with other hematologic malignancies is even rarer. We des
cribe two cases of familial HCL syndromes: a mother and son with HCL,
and a HCL patient whose aunt developed Hodgkin's Disease (HD). This is
the first reported familial association of HCL with HD.