AROMATIC ANNULATION OF ALICYCLIC ALPHA,BETA-UNSATURATED ALDEHYDES - SYNTHESIS OF CHIRALLY SUBSTITUTED TETRAHYDRONAPHTHALENES

Authors
BRENNA E FUGANTI C SERRA S
Citation
E. Brenna et al., AROMATIC ANNULATION OF ALICYCLIC ALPHA,BETA-UNSATURATED ALDEHYDES - SYNTHESIS OF CHIRALLY SUBSTITUTED TETRAHYDRONAPHTHALENES, Synlett, (4), 1998, pp. 365
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
4
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):4<365:AAOAAA>2.0.ZU;2-R
Abstract
Chiral 2-tetrahydronaphthalene-carboxylic acid derivatives 3, 6, and 9 were prepared by functionalization of enantiopure terpenic unsaturate d aldehydes 1, 4, 7 with l-(alpha-carbethoxy-beta-carboxyethyl)-phosph onium betaine, followed by a cyclization reaction promoted by ethyl ch loroformate under basic conditions.