A CONVENIENT SYNTHESIS OF 1,2,3-TRIAZOLE WITH GLYOXAL

Authors
HARADA K ODA M MATSUSHITA A SHIRAI M
Citation
K. Harada et al., A CONVENIENT SYNTHESIS OF 1,2,3-TRIAZOLE WITH GLYOXAL, Synlett, (4), 1998, pp. 431
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
4
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):4<431:ACSO1W>2.0.ZU;2-4
Abstract
A new synthetic method of 1,2,3-triazole from glyoxal monohydrazone mo no-oxime (1a) has been developed. 1a obtained by the thermal dispropor tionation of glyoxal bis-hydrazone (1b) and glyoxime (1c) was treated with acetic anhydride to give 2-acetyl-1,2,3-triazole, following alcoh olysis gave 1,2,3-triazole in high yield.