In. Smetanina et al., FEASIBILITY OF DOBUTAMINE STRESS TEST ON THE 3RD WEEK OF MYOCARDIAL-INFARCTION - COMPARISON WITH RESULTS OF BICYCLE EXERCISE TEST, Kardiologia, 38(3), 1998, pp. 12-17
High dose dobutamine stress test (up to 50 mu g/kg/min with atropine w
hen necessary) with echocardiographic and ECC control was performed in
124 patients with myocardial infarction (Q-wave -83,2%) between days
12 and 23 after onset of symptoms. Results of the test were positive i
n 50,8% (63 of 124), negative - in 45,2% and uninformative - in 4% of
patients. In 17 of 63 patients with positive tests signs of ischemia a
ppeared on 40 and in 96 patients - on 50 mu g/kg/min. The following co
mplications occurred: ventricular fibrillation - in 1 patient (success
fully resuscitated), nonsustained ventricular tachycardia - in 5, supr
aventricular arrhythmia-in 12, attacks of atrial fibrillation - in 3 p
atients. After dobutamine test all medications were resumed and routin
e predischarge bicycle exercise test with ECC control scheduled. Exerc
ise test was actually done in 79 patients (63,7%) who had no contraind
ications and were able and willing to pedal ergometer a rule in 1 day
after dobutamine infusion. Comparison of results of bicycle exorcise a
nd echocardiographic dobutamine stress tests in these patients showed
that the latter more frequently revealed myocardial ischemia (in 26,7
and 55,7% of patients respectively). Thus on the third week of myocard
ial infarction echocardiographic dobutamine stress test compared to a
bicycle exercise test with ECG control can be done in higher number of
patients, more often produces myocardial ischemia but bears a potenti
al of causing serious cardiac arrhythmia.