OPTIMIZING FREQUENCY AND NUMBER OF CONTROLS FOR AUTOMATIC MULTICHANNEL ANALYZERS

Citation
A. Neubauer et al., OPTIMIZING FREQUENCY AND NUMBER OF CONTROLS FOR AUTOMATIC MULTICHANNEL ANALYZERS, Clinical chemistry, 44(5), 1998, pp. 1014-1023
Citations number
22
Categorie Soggetti
Medical Laboratory Technology
Journal title
ISSN journal
00099147
Volume
44
Issue
5
Year of publication
1998
Pages
1014 - 1023
Database
ISI
SICI code
0009-9147(1998)44:5<1014:OFANOC>2.0.ZU;2-H
Abstract
Sampling strategy fundamentally influences the effectiveness of qualit y control with control charts. This study shows a simple approach for optimizing the control strategy for automatic multichannel analyzers t hat takes into account cost-efficiency considerations. Our main focus is on the frequency of controls necessary. The methods used are based on a field study (on a Hitachi/BM 747), the views of experts, and comp uter simulations of customary cost-models together with a survey of th e literature. We found that industrial cost-models are applicable only with distinct limitations, but-unlike the test-yield model-they offer consistent solutions. On the basis of the field study and the opinion s of experts, we adjusted the control strategy to account for inadequa cies in the theoretical models. The combined result is that, for effec tive operation, the number of samples between controls may reach value s up to 100 and should not require controls more often than every 30 s amples on comparable multichannel analyzers. For adequate statistical performance, a simple 3-SD Shewhart chart usually requires not more th an two controls of the same material at each time.