Background: Onychomycosis impairs normal nail functions, causes consid
erable pain, interferes with daily activities, and has negative psycho
social effects. Objective: Our purpose was to determine patients' perc
eption of onychomycosis on the quality of life. Methods: A total of 25
8 patients with confirmed onychomycosis were surveyed by telephone at
three centers. Responses to a standardized quality-of-life questionnai
re were analyzed for patient demographics, physical and functional imp
act, psychosocial impact, and economic impact Results: Highest positiv
e responses were nail-trimming problems (76%), embarrassment (74%), pa
in (48%), nail pressure (40%), and discomfort wearing shoes (38%). Abi
lity to pick up small objects was impaired in 41% of subjects with fin
gernail involvement. More than 58 onychomycosis-related sick days and
468 medical visits (1.8 per subject) were reported during a B-month pe
riod. Conclusion: Onychomycosis has significant social? psychologic, h
ealth, and occupational effects. Relevance of quality-of-life issues t
o overall health, earning potential, and social functioning should pro
mpt reconsideration of the value of aggressive treatment of and financ
ial coverage for onychomycosis.