FUNCTIONAL magnetic resonance imaging was used to determine the activa
tion of the amygdala while seven social phobics and five healthy contr
ols were exposed to slides of neutral faces as well as aversive odor s
timuli. The amygdala was selectively activated in the social phobics d
uring presentation of the face stimuli. The data show for the first ti
me that the amygdala is active in human phobics when they are exposed
to potentially fear-relevant stimuli. Further research is needed to de
termine the extent to which overactivation of the amygdala precedes or
is a consequence of phobia. (C) 1998 Rapid Science Ltd.