In a prospective, open study, 78 patients with terminal cancer receive
d proctoclysis (rectal hydration) in four different centers. In all ca
ses, a #22 French nasogastric catheter was inserted approximately 40 c
m into the rectum and an infusion of normal saline (2 cases) or tap wa
ter (76 cases) was administered at a rate of 250 +/- 63 cc/hr. Hydrati
on was maintained for 15 +/- 8 days. The main reason for discontinuati
on of hydration was death (60 cases). The mean visual analogue score f
or discomfort after infusion (0 = no discomfort, 100 = worst possible
discomfort) was 19 +/- 14. The costs of proctoclysis was estimated at
Can$0.08 compared with Can$4.56 per day for hypodermoclysis, and Can$2
.78 per day for intravenous hydration. Our results suggest that procto
clysis is a safe effective, and low-cost technique for the delivery of
hydration in terminally ill cancer patients. (C) U.S. Cancer Pain Rel
ief Committee 1998.