CHEMICAL TRANSGLYCOSYLATION OF FUNCTIONAL BIOACTIVE GLYCO-LINKAGES

Authors
IKEDA T KAJIMOTO T KINJO J NAKAYAMA K NOHARA T
Citation
T. Ikeda et al., CHEMICAL TRANSGLYCOSYLATION OF FUNCTIONAL BIOACTIVE GLYCO-LINKAGES, Tetrahedron letters, 39(21), 1998, pp. 3513-3516
Citations number
17
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
21
Year of publication
1998
Pages
3513 - 3516
Database
ISI
SICI code
0040-4039(1998)39:21<3513:CTOFBG>2.0.ZU;2-V
Abstract
The natural functional bioactive oligosaccharides moieties, mimosatetr aose and fabatriose, were cut off from julibrosides and soyasaponin I by chemical and enzymatic methods, respectively, and were pasted to di osgenin to give neosaponins 1 and 2. The obtained neosaponins were tes ted for cytotoxicity and hepatoprotective activity. This method could be applied to the synthesis of novel bioactive glycosides. (C) 1998 El sevier Science Ltd. All rights reserved.