NON-HODGKINS-LYMPHOMA PRESENTING WITH ADRENAL INSUFFICIENCY AND HYPOTHYROIDISM - AN AUTOPSY CASE-REPORT

A 55-year-old male presented with an initial manifestation of primary adrenal insufficiency, hypothyroidism. Computed tomography scans showe d enlarged bilateral adrenal glands and thyroid. A pathological diagno sis of diffuse large cell, B cell lymphoma was made by a needle biopsy of the adrenal gland. He was treated with combination chemotherapy an d adrenal and thyroid hormone replacement. The lymphoma subsequently i nvolved the central nervous system. He died of pneumonia 8 months afte r the presentation of the first symptom. The postmortem examination de monstrated a complete regression of lymphoma in the bilateral adrenal glands and thyroid. This is an extremely rare case of coexistent lymph oma of the adrenal glands and the thyroid presenting with adrenal fail ure and hypothyroidism.