BIOELECTROCHEMICALLY ACCELERATED MICROBIAL CONVERSION OF NICOTINIC-ACID TO 6-HYDROXYNICOTINIC ACID ON MICROORGANISM-IMMOBILIZED COLUMN ELECTROLYTIC FLOW SYSTEM

Authors
TORIMURA M YOSHIDA H KANO K IKEDA T NAGASAWA T UEDA T
Citation
M. Torimura et al., BIOELECTROCHEMICALLY ACCELERATED MICROBIAL CONVERSION OF NICOTINIC-ACID TO 6-HYDROXYNICOTINIC ACID ON MICROORGANISM-IMMOBILIZED COLUMN ELECTROLYTIC FLOW SYSTEM, Chemistry Letters, (4), 1998, pp. 295-296
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Chemistry Letters → ACNP
ISSN journal
03667022
Issue
4
Year of publication
1998
Pages
295 - 296
Database
ISI
SICI code
0366-7022(1998):4<295:BAMCON>2.0.ZU;2-8
Abstract
Nicotinic acid (NA) is efficiently hydroxylated into 6-hydroxynicotini c acid (6HNA) by Pseudomonas fluorescens TN5-immobilized column electr olytic method using K3Fe(CN)(6) as an extracellular electron transfer mediator, in which the conversion rate was sufficiently accelerated co mpared with the aerobic oxidation. The NA conversion system was applie d to the continuous-production of 6HNA in 100% yield and the absolute determination of NA in flow-injection analysis.