ENANTIOSELECTIVITY IN THE REDUCTION OF TRICYCLIC HYDROAROMATIC KETONES BY BAKERS-YEAST

Authors
FONTANA G MANITTO P SPERANZA G ZANZOLA S
Citation
G. Fontana et al., ENANTIOSELECTIVITY IN THE REDUCTION OF TRICYCLIC HYDROAROMATIC KETONES BY BAKERS-YEAST, Tetrahedron : asymmetry, 9(8), 1998, pp. 1381-1387
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
8
Year of publication
1998
Pages
1381 - 1387
Database
ISI
SICI code
0957-4166(1998)9:8<1381:EITROT>2.0.ZU;2-K
Abstract
Three benzo-2-tetralones were hydrogenated to the corresponding alcoho ls by non-fermenting baker's yeast. Satisfactory yields but modest ena ntioselectivities were observed. The prevalent enantioform of the benz o-2-tetralol was found to be in agreement with the predictive abstract model previously proposed for the enzymatic hydrogenation of aromatic ring substituted 2-tetralones. (C) 1998 Elsevier Science Ltd. All rig hts reserved.