DYNAMIC CHANGES OF 12-LEAD ELECTROCARDIOGRAMS IN A PATIENT WITH BRUGADA-SYNDROME

Dynamic ECG Changes in Brugada Syndrome. We present a patient with Bru gada syndrome in whom 12-lead ECGs were recorded just before and after an episode of ventricular fibrillation (VF). A progressive elevation of both the RS-T segment and J waves just preceding and following the VF, and a close relationship between the amplitude of the RS-T segment and the preceding R-R intervals during atrial fibrillation, were docu mented, These findings support the hypothesis that RS-T elevation and a subsequent VF are related to a transient outward current-mediated sp ike-and-dome morphology of the epicardial action potential.