ENANTIOSELECTIVE APPROACH TO THE SYNTHESIS OF CYCLOHEXANE CARBOCYCLICNUCLEOSIDES

(R)-(-)-Carvone was used as starting material for the synthesis of a n ew series of 2-(hydroxymethyl)cyclohexane-1,3-diol nucleosides. The en antioselective precursors of the nucleoside analogues were obtained vi a a stereo-and regioselective hydroboration reaction. The compounds ha ve equatorial oriented base moieties despite the presence of three oth er axial substituents.