Sj. Sowerby et Wm. Heckl, THE ROLE OF SELF-ASSEMBLED MONOLAYERS OF THE PURINE AND PYRIMIDINE-BASES IN THE EMERGENCE OF LIFE, Origins of life and evolution of the biosphere, 28(3), 1998, pp. 283-310
The experimental evidence for the spontaneous formation and structure
determination of two-dimensional monolayers of the purine and pyrimidi
ne bases is examined. The plausibility of such structures forming spon
taneously at the solid-liquid interface following their prebiotic synt
hesis suggests a functional role for them in the emergence of life. It
is proposed that prebiotic interactions of enantiomorphic monolayers
of mixed base composition with racemic amino acids might be implicated
in a simultaneous origin of a primitive genetic coding mechanism and
biomolecular homochirality. The interactions of these monolayers with
carbohydrates and other derivatives is also discussed.