Histologic examination of the human myocardium has been performed seve
ral days, weeks, and months after transmyocardial laser revascularizat
ion. We performed microscopic examinations 2 hours postoperatively. In
addition to the patent channel (diameter, 1 mm) and a 1- to 2-mm rim
of necrosis, a 1- to 3-mm zone of myofibrillary degeneration was found
. This additional reversible injury immediately after transmyocardial
laser revascularization could explain the higher mortality rate in pat
ients with reduced left ventricular function. (C) 1998 by The Society
of Thoracic Surgeons.