Descending cervical mediastinitis is an uncommonly reported presentati
on of infection originating in the head or neck and descending into th
e mediastinum, which is fraught with impressive morbidity and mortalit
y rates of 30% to 40% or more. We present the INOVA-Fairfax-Alexandria
Hospital experience with descending cervical mediastinitis, January 1
, 1986, to April 1, 1997; in addition we review the English-language m
edical and surgical literature with regard to this entity. Computed to
mography and magnetic resonance imaging serve to aid both diagnosis an
d management. The application of broad-spectrum antibiotics should ini
tially be empiric, with an eye to coverage of mixed aerobic and anaero
bic infections. Definitive treatment mandates early and aggressive sur
gical intervention. All affected tissue planes, cervical and mediastin
al, must be widely debrided, often leaving them open for frequent pack
ing and irrigation. The treating physician must remain always alert to
the further extension of infection, which, if it occurs, must be furt
her debrided and drained. Tracheostomy serves a dual role of further o
pening cervical fascial planes and securing an often compromised airwa
y. (C) 1998 by The Society of Thoracic Surgeons.