BUERGERS-DISEASE IN 2 BROTHERS - ILIAC ARTERY-OCCLUSION BY THROMBOANGIITIS-OBLITERANS - CASE-REPORTS

Several characteristics of thromboangiitis obliterans are unique and c onfirm the existence of the disease as a distinct pathological entity. Its predilection for young smoking males, peripheral type of vascular involvement, recurrences of superficial thrombophlebites, and typical histolopathology form the principals of the disease although the etio logy remains unknown. The authors report the unusual finding of Buerge r's disease occurring in two brothers, one of whom had occlusion of th e left external iliac and femoral arteries. All other clinical charact eristics of these two cases were typical for thromboangiitis obliteran s. Presentation of some peculiarities of the disease, particularly the lack of familial association, may help to unravel the pathogenesis of thromboangiitis obliterans.