EFFECT OF OXINDOLE ALKALOIDS FROM THE HOOKS OF UNCARIA-MACROPHYLLA ONTHIOPENTAL-INDUCED HYPNOSIS

Citation
I. Sakakibara et al., EFFECT OF OXINDOLE ALKALOIDS FROM THE HOOKS OF UNCARIA-MACROPHYLLA ONTHIOPENTAL-INDUCED HYPNOSIS, Phytomedicine, 5(2), 1998, pp. 83-86
Citations number
8
Categorie Soggetti
Pharmacology & Pharmacy","Plant Sciences
Journal title
ISSN journal
09447113
Volume
5
Issue
2
Year of publication
1998
Pages
83 - 86
Database
ISI
SICI code
0944-7113(1998)5:2<83:EOOAFT>2.0.ZU;2-9
Abstract
Four tetracyclic oxindole alkaloids, rhynchophylline, isorhynchophylli ne, corynoxine and corynoxine B were isolated from the hooks of Uncari a marcrophylla Wall. (Rubiaceae), that is a dominant plant widely dist ributed in Yunnan province. These compounds exhibited prolongation of the thiopental-induced hypnosis on oral administration in mice.