I. Sakakibara et al., EFFECT OF OXINDOLE ALKALOIDS FROM THE HOOKS OF UNCARIA-MACROPHYLLA ONTHIOPENTAL-INDUCED HYPNOSIS, Phytomedicine, 5(2), 1998, pp. 83-86
Four tetracyclic oxindole alkaloids, rhynchophylline, isorhynchophylli
ne, corynoxine and corynoxine B were isolated from the hooks of Uncari
a marcrophylla Wall. (Rubiaceae), that is a dominant plant widely dist
ributed in Yunnan province. These compounds exhibited prolongation of
the thiopental-induced hypnosis on oral administration in mice.