TRANSCRIPTION OF CHROMATIN - THESE ARE COMPLEX TIMES

Authors
ARMSTRONG JA EMERSON BM
Citation
Ja. Armstrong et Bm. Emerson, TRANSCRIPTION OF CHROMATIN - THESE ARE COMPLEX TIMES, Current opinion in genetics & development, 8(2), 1998, pp. 165-172
Citations number
59
Categorie Soggetti
Biology,"Cell Biology","Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
Current opinion in genetics & development → ACNP
ISSN journal
0959437X
Volume
8
Issue
2
Year of publication
1998
Pages
165 - 172
Database
ISI
SICI code
0959-437X(1998)8:2<165:TOC-TA>2.0.ZU;2-Z
Abstract
Transcription of chromatin-packaged genes involves highly regulated ch anges in nucleosomal structure that control DNA accessibility. Two sys tems that facilitate these changes are ATP-dependent chromatin remodel ing complexes and enzymatic complexes which control histone acetylatio n and deacetylation. Recent studies provide insight on the role of the se remodeling machines and specific transcription factors in the expre ssion of viral, inducible, and tissue-restricted genes. (C) Current Bi ology Ltd ISSN 0959-437X.