COVALENT MODIFICATIONS OF HISTONES - EXPRESSION FROM CHROMATIN TEMPLATES

Authors
DAVIE JR
Citation
Jr. Davie, COVALENT MODIFICATIONS OF HISTONES - EXPRESSION FROM CHROMATIN TEMPLATES, Current opinion in genetics & development, 8(2), 1998, pp. 173-178
Citations number
57
Categorie Soggetti
Biology,"Cell Biology","Biothechnology & Applied Migrobiology","Genetics & Heredity
Journal title
Current opinion in genetics & development → ACNP
ISSN journal
0959437X
Volume
8
Issue
2
Year of publication
1998
Pages
173 - 178
Database
ISI
SICI code
0959-437X(1998)8:2<173:CMOH-E>2.0.ZU;2-9
Abstract
Recent advances highlight the involvement of histone acetyltransferase s in transcriptional activation and histone deacetylases in transcript ional repression. Transcription factors roaded onto regulatory DNA ele ments may recruit either coactivators with histone acetyltransferase a ctivity or corepressors associated with histone deacetylases. The recr uited enzymes may either acetylate or deacetylate proximal nucleosomal histones or nonhistone chromosomal proteins. (C) Current Biology Ltd ISSN 0959-437X.