DEVELOPMENT OF A BIOASSAY EMPLOYING THE DESERT LOCUST (SCHISTOCERCA-GREGARIA) FOR THE DETECTION OF SAXITOXIN AND RELATED-COMPOUNDS IN CYANOBACTERIA AND SHELLFISH

Authors
MCELHINEY J LAWTON LA EDWARDS C GALLACHER S
Citation
J. Mcelhiney et al., DEVELOPMENT OF A BIOASSAY EMPLOYING THE DESERT LOCUST (SCHISTOCERCA-GREGARIA) FOR THE DETECTION OF SAXITOXIN AND RELATED-COMPOUNDS IN CYANOBACTERIA AND SHELLFISH, Toxicon, 36(2), 1998, pp. 417-420
Citations number
10
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Toxicon → ACNP
ISSN journal
00410101
Volume
36
Issue
2
Year of publication
1998
Pages
417 - 420
Database
ISI
SICI code
0041-0101(1998)36:2<417:DOABET>2.0.ZU;2-V
Abstract
Monitoring paralytic shellfish toxins (PST) in shellfish and freshwate r cyanobacteria is largely dependent on the mouse bioassay. An alterna tive assay was devised using the desert locust Schistocerca gregaria. The bioassay successfully identified the optimum extraction procedure for PST from cyanobacterial cells and was also suitable for screening acid extracts of shellfish flesh. These results demonstrate the potent ial of the locust bioassay for the routine screening of PST in a range of sample matrices. (C) 1998 Elsevier Science Ltd. All rights reserve d.