COMPARISON OF ANTIHEMORRHAGIC ACTIVITIES IN SKELETAL-MUSCLE EXTRACTS FROM VARIOUS ANIMALS AGAINST BOTHROPS-JARARACA SNAKE-VENOM

Authors
OMORISATOH T TAKAHASHI M NAGAOKA Y MEBS D
Citation
T. Omorisatoh et al., COMPARISON OF ANTIHEMORRHAGIC ACTIVITIES IN SKELETAL-MUSCLE EXTRACTS FROM VARIOUS ANIMALS AGAINST BOTHROPS-JARARACA SNAKE-VENOM, Toxicon, 36(2), 1998, pp. 421-423
Citations number
18
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Toxicon → ACNP
ISSN journal
00410101
Volume
36
Issue
2
Year of publication
1998
Pages
421 - 423
Database
ISI
SICI code
0041-0101(1998)36:2<421:COAAIS>2.0.ZU;2-0
Abstract
Antihemorrhagic activities of skeletal muscle extracts from various an imals were compared in inhibiting the hemorrhagic activity of Bothrops jararaca venom. The muscle extracts of the European hedgehog (Erinace us europaeus) exhibited the strongest activity, followed by those of o ther insectivores such as the shrew (Crocidura russula) and mole (Talp a europaea). The antihemorrhagic activities of muscle extracts from ex perimental animals such as mice, rats, guinea-pigs, hamsters and rabbi ts were negligible. (C) 1998 Elsevier Science Ltd. All rights reserved .