Mc. Caminada et al., ACUTE EXACERBATED LUPUS-ERYTHEMATOSUS - D IFFERENTIAL-DIAGNOSIS OF A HELLP-SYNDROME, Geburtshilfe und Frauenheilkunde, 58(4), 1998, pp. 225-227
The term HELLP-syndrome was inaugurated by Weinstein in 1982 and is ch
aracterised by the following trias in patients with pregnancy-induced
hypertonia (PIH): haemolysis, elevated liver enzymes, low platelets. I
n recent years cases of ''incomplete'' HELLP-syndrome have been report
ed which lack some of the symptoms. With increasing awareness of this
disease among obstetricians the reported incidence is increasing. Undo
ubtedly some patients are misclassified as having HELLP-syndrome and c
onsequently receive inadequate therapy. Other pregnancy-induced altera
tions or selected diseases in internal medicine may mimick symptoms of
HELLP-syndrome. To stress the necessity for considering differential
diagnoses in patients with HELLP-syndrome, we report on the following
clinical observation. A 23-year old patient was referred to our hospit
al under diagnosis of HELLP-syndrome during her 33 + 2(nd) week of ges
tation. Because of a pathologic cardiotocogram and urgent C-section wa
s performed. After birth the patient was diagnosed of having a systemi
c Lupus erythematosus which was aggravated during pregnancy.