HIV ANTIBODY SEROPREVALENCE AND ASSOCIATED RISK-FACTORS IN SEX WORKERS, DRUG-USERS, AND PRISONERS IN SINDH, PAKISTAN

Objective: To determine prevalence of HIV infection and risk behaviors in commercial sex workers (CSWs), drug users, and prisoners in Sindh, Pakistan. Methods: A medical clinic was established in a ''red-light' ' district of Karachi. Eighty-one CSWs who registered at the clinic be tween November 1993 and June 1994 were provided HIV counseling and tes ting and administered a risk factor questionnaire. Next, 316 male drug users were tested for HIV-1 antibody from April to July 1994. Finally , a voluntary serosurvey of HIV-1 and HIV-2 and risk behaviors of 3525 prisoners in Sindh was conducted between July 1994 and December 1994. Abbott Recombinant HIV third-generation enzyme-linked immunosorbent a ssay (ELISA) and confirmatory testing with Western blot analysis were used in all three groups. Results: None of 81 CSWs tested for HIV-1 an tibody were positive. None of 316 drug users tested positive for HIV-1 antibody. Of 3441 male prisoners, 1 was HIV-I infected, and of 84 fem ale prisoners, 1 was HIV-1 infected. No prisoner was positive for HIV- 2 antibody. Discussion: The prevalence of HIV in CSWs, drug users, and prisoners in Sindh is low at present. Intervention programs implement ed at this stage can make an impact in HIV prevention.