NEW BIOCIDAL N-HALAMINE-PEG POLYMERS

Citation
Mw. Eknoian et al., NEW BIOCIDAL N-HALAMINE-PEG POLYMERS, Journal of bioactive and compatible polymers, 13(2), 1998, pp. 136-145
Citations number
22
Categorie Soggetti
Polymer Sciences","Biothechnology & Applied Migrobiology","Materials Science, Biomaterials
ISSN journal
08839115
Volume
13
Issue
2
Year of publication
1998
Pages
136 - 145
Database
ISI
SICI code
0883-9115(1998)13:2<136:NBNP>2.0.ZU;2-8
Abstract
The synthesis and biocidal efficacies of two PEG-N-halamine polymers w ere reported. The N-halamines are classified as dichlorohydantoins and chloroimidazolidin-4-ones, which were attached to a methoxy-poly(ethy lene glycol) terminated amine. A 1000 ppm solution of each N-halamine polymer was prepared in water and it was demonstrated that Staphylococ cus aureus was inactivated (6 logs) when it was in contact with these polymeric solutions for ten minutes. The stability of these solutions was determined over prolonged periods of time, as well as the biocidal efficacies. These polymeric materials show commercial potential as su rface active biocides if the poly(ethylene glycol) moiety can be ancho red to a surface.