Aa. Bialasiewicz et al., INTRAOCULAR PSEUDOTUMOR IN A PATIENT WITH AIDS - BLOCK EXCISION, DIFFERENTIAL-DIAGNOSIS, HISTOLOGY, Der Ophthalmologe, 95(4), 1998, pp. 229-232
Background: Intraocular pseudotumors are a rare event in Aids patients
and often pose diagnostic problems. Case report: A 37-year-old patien
t who had had HIV seroconversion for 7 years was seen to developed pro
gressively growing, multiple, disseminated, subretinal lesions OD > OS
, accompanied by exudative retinal detachment and iritis. Since all et
iological laboratory diagnostic efforts to detect an infectious, nonin
fectious and neoplastic systemic lesion failed, a diagnostic and curat
ive therapeutic chorioretinal excisional biopsy specimen of the larges
t of the tumors (3 x 3 x 2 mm) was taken. The histological work-up dem
onstrated granulation tissue similar to an intracular pseudotumor with
out signs of infection, malignancy or reactive lymphoid hyperplasia. T
his finding resulted in systemic corticosteroid treatment with complet
e resolution of the lesions in both eyes and no recurrences. Conclusio
ns: An invasive diagnostic procedure in patients suffering from lesion
s of unknown cause resulting in the institution of an appropriate medi
cal treatment may be beneficial for the integrity and vision of the re
spective eye.