PRIMARY ALDOSTERONISM AND ADRENOCORTICAL ADENOMA - SUPPRESSION OF PLASMA-ALDOSTERONE WITH DEXAMETHAZONE

Authors
BERCOVICI JP ROUDAUT N KERLAN V AUPETITFAISANT B FLOCH HH
Citation
Jp. Bercovici et al., PRIMARY ALDOSTERONISM AND ADRENOCORTICAL ADENOMA - SUPPRESSION OF PLASMA-ALDOSTERONE WITH DEXAMETHAZONE, Annales d'Endocrinologie, 59(1), 1998, pp. 20-22
Citations number
7
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Annales d'Endocrinologie → ACNP
ISSN journal
00034266
Volume
59
Issue
1
Year of publication
1998
Pages
20 - 22
Database
ISI
SICI code
0003-4266(1998)59:1<20:PAAAA->2.0.ZU;2-L
Abstract
The aim of the study was to evaluate dexamethazone test in a patient w ith primary aldosteronism caused by an adrenocortical adenoma. We obse rved a 50% decrease of plasma aldosterone as in glucocorticoid suppres sible aldosteronism (GSA) but absolute value of aldosterone remained h igher than 40 pg/ml. Basal plasma and urinary values of 18 OXO and 18 OH cortisol were not significantly elevated as in GSA. Inversely, the evaluation of 11 beta-hydroxylase activity of mineralocorticoids was i n favor of a benign adrenal tumor.