PRIMARY ADRENAL LYMPHOMA WITH LATENT ADRE NAL INSUFFICIENCY - A CASE-REPORT AND REVIEW OF THE LITERATURE

Primary adrenal lymphoma with latent adrenal insufficiency : a case re port and review of the literature. We report a new case of primary adr enal lymphoma with latent adrenal insufficiency and long-term remissio n after hydrocortisone replacement therapy. We have analyzed 29 other cases described in the literature. This disease with poor prognosis ca n be revealed by an incidentally discovered, frequently bilateral, adr enal mass. Adrenal insufficiency may be latent and the diagnostic proc edure should include both cortisol and ACTH determination with an addi tional ACTH stimulation test if appropriate. Early adrenal substitutio n can improve patient survival.