INCORPORATION OF ALPHA-TRIFLUOROMETHYL SUBSTITUTED ALPHA-AMINO-ACIDS INTO C-TERMINAL AND N-TERMINAL POSITION OF PEPTIDES AND PEPTIDE MIMETICS USING MULTICOMPONENT REACTIONS

Authors
BURGER K MUTZE K HOLLWECK W KOKSCH B
Citation
K. Burger et al., INCORPORATION OF ALPHA-TRIFLUOROMETHYL SUBSTITUTED ALPHA-AMINO-ACIDS INTO C-TERMINAL AND N-TERMINAL POSITION OF PEPTIDES AND PEPTIDE MIMETICS USING MULTICOMPONENT REACTIONS, Tetrahedron, 54(22), 1998, pp. 5915-5928
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
22
Year of publication
1998
Pages
5915 - 5928
Database
ISI
SICI code
0040-4020(1998)54:22<5915:IOASAI>2.0.ZU;2-6
Abstract
Methodology for incorporation of alpha-trifluoromethyl substituted ami no acids into the C- and N-terminal position of peptides and peptide m imetics via multicomponent reactions of the Passerini and Ugi type is described. (C) 1998 Elsevier Science I,td. All rights reserved.