SERUM GELSOLIN AND RHABDOMYOLYSIS

We measured the serum gelsolin, actin-modulating protein, levels in fi ve patients after rhabdomyolysis. We observed a tendency of serum gels olin (83 kDa) to increase during the study period of 11 days. No intra cellular gelsolin (80 kDa) was found in the serum, although it is abun dant in muscle, and the destruction was severe as judged by other para meters. Serum gelsolin thus behaves differently in rhabdomyolysis than after acute tissue damage in other organs, such as liver necrosis and adult respiratory distress syndrome. (C) 1998 Elsevier Science B.V.