LEUKEMOGENESIS - SMALL DIFFERENCES IN MYB HAVE LARGE EFFECTS

Authors
GRAF T
Citation
T. Graf, LEUKEMOGENESIS - SMALL DIFFERENCES IN MYB HAVE LARGE EFFECTS, Current biology, 8(10), 1998, pp. 353-355
Citations number
15
Categorie Soggetti
Biology,Biology
Journal title
Current biology → ACNP
ISSN journal
09609822
Volume
8
Issue
10
Year of publication
1998
Pages
353 - 355
Database
ISI
SICI code
0960-9822(1998)8:10<353:L-SDIM>2.0.ZU;2-5
Abstract
The avian retroviruses E26 and AMV carry mutated versions of the gene encoding the cellular transcription factor c-Myb. Surprisingly, these two mutant forms of Myb differ in the subsets of myeloid cells that th ey transform, the target genes that they activate, and the way in whic h they are regulated. (C) Current Biology Ltd ISSN 0960-9822.