Purpose: Our purpose was to analyze the CT findings of neural plexus i
nvasion in common bile duct carcinoma. Method: We studied 16 patients
with common bile duct carcinoma who underwent surgery. Of these, neura
l invasion was seen in 10 patients. CT findings were retrospectively r
eviewed and correlated with the surgical and pathological findings. Re
sults: Irregular masses adjacent to the medial aspect of the uncinate
process were observed in 4 of 14 patients with distal common bile duct
carcinoma. These lesions extended medially and showed contiguity with
the superior mesenteric artery and/or celiac axis, corresponding to n
eural plexus invasion with desmoplastic change. Increased attenuation
of the fat between the common bile duct and the proper hepatic artery
was seen in two of two patients with proximal common bile duct carcino
ma, associated with neural plexus invasion in the hepatoduodenal ligam
ent. Conclusion: The location and spread of neural plexus invasion in
common bile duct carcinoma are characteristic and can be diagnosed by
CT.